PT-141

PT-141

$285

PT-141 (Bremelanotide) offers a unique approach to enhancing libido by targeting brain pathways involved in sexual arousal, providing an option for men and women experiencing low sexual desire. Unlike medications that affect blood flow, PT-141 works directly in the brain to stimulate desire.

Key Benefits

  • Increases sexual desire and libido
  • Enhances sexual arousal and interest
  • Works for both men and women
  • Central nervous system–based mechanism
  • Alternative when PDE5 inhibitors are ineffective

PT-141,   also   known   as   Bremelanotide,   is   a   synthetic   peptide   analog   of   alpha-Melanocyte   Stimulating   Hormone   (α-MSH).   It   binds   to   melanocortin   receptors   in   the   brain,   activating   pathways   responsible   for   sexual   desire   and   arousal. This   treatment   is   particularly   helpful   for   individuals   with   Hypoactive   Sexual   Desire   Disorder   (HSDD)   or   arousal   difficulties   that   aren’t   related   to   relationship   issues   or   medical   side   effects.   It   offers   a   discreet   and   effective   solution   when   traditional   treatments   fail   or   are   not   suitable.

PT-141

Who Can Benefit from PT-141?

PT-141 is primarily indicated for individuals experiencing low sexual desire (Hypoactive Sexual Desire Disorder - HSDD) not caused by relationship issues, medical conditions, or medication side effects. It is particularly useful for those who have not responded well to other libido-enhancing treatments or who seek a more natural, brain-based mechanism for enhancing desire.

1

Low or absent sexual desire/libido

PT-141 may benefit individuals experiencing a persistent lack of interest in sex that causes personal distress. Its brain-based mechanism directly stimulates sexual motivation pathways.

2

Decreased interest in sexual activity

Those who have noticed a significant decline in their interest or motivation for intimacy may find PT-141 helpful in restoring a natural sense of desire and engagement.

3

Lack of sexual thoughts or fantasies

If sexual thoughts or fantasies have become infrequent or absent, PT-141 may help by increasing dopamine activity in brain regions related to mental arousal and anticipation.

4

Difficulty achieving arousal

Individuals who struggle to become aroused despite stimulation or willingness may benefit from PT-141’s unique action on arousal-related brain centers.

Mechanism of Action

PT-141 is a melanocortin receptor agonist that activates MC3-R and MC4-R receptors in the central nervous system. It increases dopamine levels and enhances neural signaling in areas of the brain responsible for sexual motivation, bypassing the vascular system entirely and working independently of hormones or blood flow.

PT-141 - How It Works

How It Works in Your Brain

Binds to melanocortin receptors MC3-R and MC4-R in the brain
Activates neural pathways involved in sexual motivation
Increases dopamine release in key brain regions
Enhances arousal via central nervous system action
Works independently of blood flow or hormonal levels
Safe for both men and women

More Sexual Health Treatments

Explore our other treatment options that may complement or offer alternatives to PT-141.

Oxytocin Therapy

Oxytocin Therapy

Hormone nasal spray or sublingual forms to potentially enhance intimacy and connection.

Tadalafil

Tadalafil

Long-acting PDE5 inhibitor for erectile dysfunction and enhanced sexual function.

Explore Our Programs

Discover more specialized treatments and services offered at Fountain

Frequently Asked Questions

Everything you need to know about PT-141 treatment

Yes, PT-141 (as Bremelanotide or Vyleesi) is FDA-approved for HSDD in premenopausal women. Off-label use in men and postmenopausal women is also common under medical supervision.
The most common side effect is nausea, followed by flushing, headache, and injection site irritation. Taking it with food or using an anti-nausea agent may reduce discomfort.
PT-141 is used as needed, not daily. Most providers recommend spacing out usage to no more than several times per week depending on individual response and tolerability.

Rekindle Desire with PT-141

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